COMPO

The Inria-Inserm COMPO joint project-team develops novel mathematical, statistical, and computational tools to model data in oncology, with a focus on clinical data from clinical studies and routine care. The team's objectives are: 1) to improve the quantitative understanding of cancer diseases, 2) to assist drug development through biomarker identification, dosing regimen optimization, and clinical trials decision support, and 3) to develop personalized medicine by providing clinicians with digital decision tools.

To achieve these goals, the team uniquely brings together mathematicians, computer scientists, pharmacologists, and medical oncologists. It is integrated into the Center of Cancer Research of Marseille (Inserm U1068, CNRS UMR7258, Aix-Marseille Université UM105, Institut Paoli-Calmettes) and located on the La Timone Health Science campus of the University Hospitals of Marseille (AP-HM), close to the INCa-labeled center for early phase clinical trials (CLIP2).

Built on strong expertise in mathematical modeling, pharmacometrics, and experimental and clinical oncology, the project-team is committed to developing novel methodologies combining mechanistic and statistical learning ("mechanistic learning") to be ultimately applied at bedside.